Technology for Isolation Essential Oil from the Buds of Populus balsamifera L.
DOI:
https://doi.org/10.18321/ectj1545Keywords:
Populus balsamifera L. buds , essential oil , technology , barothermal isolation method, pilot industrial regulations , pharmacological studyAbstract
The article presents the results of the development of technology for isolating essential oil from the buds of Populus balsamifera L. and a medicinal substance based on it. For the first time, a technology has been developed for the quantitative isolation of essential oil from the buds of Populus balsamifera L. by the barothermal method at a temperature of 140 ºC, under a vacuum of 1333‒2000 Pa. The main components of the essential oil of Populus balsamifera L. buds, isolated by the barothermal method, were determined to be α-bisabolol, β-eudesmol, and 2-phenylethyl-2-methylbutanoate. A technological scheme for the production of essential oil substance from Populus balsamifera L. buds has been developed, including 2 stages of the main technological process and 2 stages of auxiliary work, and its pilot industrial regulations. The control points during the isolation and preparative production of the essential oil substance from the Populus balsamifera L. buds are the major components α-bisabolol and β-eudesmol. The main critical points in the production of a substance based on the essential oil of Populus balsamifera L. buds are pressure, temperature, and duration of isolation. The stages of production of the substance are controlled using a standard sample of α-bisabolol (1). A quantitative determination of 108 components of essential oil from Populus balsamifera L. buds was carried out, as well as standardization for organoleptic properties and major components. A comparative analysis of essential oil from Populus balsamifera L. buds collected in the vicinity of Karaganda and the North Kazakhstan region was carried out. A substance based on essential oil from Populus balsamifera L. buds has antimicrobial, wound-healing, and antitumor activities with relatively low toxicity.
References
(1). I.A. Schepetkin, G. Özek, T. Özek, L.N. Kirpotina, et al., Plants 11 (2022) 3399–3419. Crossref
(2). V.A. Isidorov, V.T Vinogorova, Zeitschrift für Naturforschung C 58 (2003) 355–360. Crossref
(3). M. Piochon-Gauthier J. Legault, M. Sylvestre, A. Pichette, Nat. Prod. Commun. 9 (2014) 257–260. Crossref
(4). E.V. Isaeva, G.A. Lozhkina, T.V. Ryazanova, A.I. Vyalkov, D.V. Domrachev, A.V. Tkachev. Chromato-mass-spectrometric study of volatile components of the vegetative part of Populus balsamifera L. Himija rastitel’nogo syr’ja [Chemistry of plant raw materials] 1 (2008) 63–66. (in Russ.) URL
(5). G. Sandner, M. Heckmann, J. Weghuber, Biomolecules 10 (2020) 1139–1155. Crossref
(6). G.R. Gandhi, A.B.S. Vasconcelos, G.H. Haran, V.K. da Silva Calisto, et al., Phytomedicine 73 (2020) 152854. Crossref
(7). G.P.P. Kamatou, A.M. Viljoen, J. Am. Oil Chem. Soc. 87 (2010) 1–7. Crossref
(8). L.B. Eddin, N.K. Jha, S.N. Goyal, Y.O. Agrawal, S.B. Subramanya, Nutrients 14 (2022) 1370. Crossref
(9). A.V. Tkachev. Issledovaniye letuchikh veshchestv rasteniy. [Study of volatile substances of plants]. Novosibirsk, 2008, 969 p. (in Russ.)
(10). State Pharmacopoeia of the Republic of Kazakhstan. Almaty: publishing house “Zhibek Zholy”, V. 1 (2008) 592 p. (in Russ.) URL
(11). R.U. Khabriev. Guide to experimental (preclinical) study of new pharmacological substances. Under the general editorship of Corresponding Member of the Russian Academy of Medical Sciences, Professor R.U. Khabriev OJSC “Publishing House “Medicine” 2005, 832 p. (in Russ.) URL
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