Study of Icaritin Films by Low-Energy Electron Beam Deposition

  • Tongfei Cheng International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei str., Nanjing 210094, China
  • Jinxing Cao International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei str., Nanjing 210094, China
  • Xiaohong Jiang International Chinese-Belorussian Scientific Laboratory on Vacuum-Plasma Technology, Nanjing University of Science and Technology, 200, Xiaolingwei str., Nanjing 210094, China
  • M.A. Yarmolenko Francisk Skorina Gomel State University, 104, Sovetskaya str., Gomel 246019, Belarus
  • A.A. Rogachev Francisk Skorina Gomel State University, 104, Sovetskaya str., Gomel 246019, Belarus
  • A.V. Rogachev Francisk Skorina Gomel State University, 104, Sovetskaya str., Gomel 246019, Belarus
Keywords: low-energy electron beam deposition, icaritin film, material characterization, film release, biocompatibility

Abstract

In this paper, icaritin film was prepared by low-energy beam electron beam deposition (EBD). The material test showed that the structure and composition of icaritin were not changed after electron beam deposition. Then, the film was sliced and immersed in simulated body fluids, it can be seen that the film was released quickly in the first 7 days. With the extension of soaking time, the release rate gradually slowed down, and the release amount exceeded 90% in about 20 days. In vitro cytotoxicity test showed that the relative cell viability rate of the film was still 92.32±1.30% (p<0.05), indicating that the film possessed excellent cytocompatibility.

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Published
2021-08-30
How to Cite
[1]
T. Cheng, J. Cao, X. Jiang, M. Yarmolenko, A. Rogachev, and A. Rogachev, “Study of Icaritin Films by Low-Energy Electron Beam Deposition”, Eurasian Chem.-Technol. J., vol. 23, no. 2, pp. 77-87, Aug. 2021.
Section
Articles

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